Wednesday, December 2, 2015

Getting a Handle on CRISPR/Cas9

One day into the International Summit on Human Gene Editing in Washington, D.C., I’m struck by how easy it is for a lay person (namely myself) to get lost in the science. That gulf in comprehension complicates the effort to earn public buy-in and trust for use of the new technology.
This summit has brought together policymakers, scientists and ethicists from China, the United Kingdom and the United States in a quite extraordinary attempt to understand and possibly assign limits to the use of emerging technologies that can be as morally troubling as they are scientifically promising. 
It was heartening to hear, early in Day 2, a call for scientists to take responsibility for helping the public understand both the profound benefits and considerable risks inherent in the new gene-editing technology.  (If “Aldous Huxley” and #BraveNewWorld are trending this week, this is why.)
The summit continues today and Thursday, and is available live via webcast.  
I’m especially looking forward to Thursday morning’s session titled “Interrogating Equity.”
What follows are a layman’s takeaways from Day 1, a webcast of which is available for viewing here
  1. Predicting outcome in a Twitter word count: Yes to treating, curing humans. No to altering humanity.
  2. When a child’s leukemia is effectively treated in a new way, there is broad public support. 
  3. Questions: When is CRISPR/Cas9 safe to use? When is it therapeutically justified? (Answer unclear as yet)
  4. To paraphrasing one presenter: Our capacity for manipulating is greater than our understanding.
  5. With gene editing, the shadow of eugenics is unmistakable & maybe unshakable.
  6. In that context, “That was then, this is now” is not a convincing argument.
  7. It took 90 minutes to hear from the first woman (Alta Charo, U of Wisconsin).
  8. The challenge of getting CRISPR/Cas9 to behave: “Off-target modifications” are at heart of concern. Translation: Beware of unintended consequences and collateral damage.
  9. Favorite moment: Physicist Jonathan Weissman of UC San Francisco likening gene editing to volume control. Weissman’s dial goes to 11. #SpinalTap @ #GeneEditSummit
  10. In helping the public understand, @pknoepfler’s blog is a good model: 
One last thought: This summit in itself is a good step on the path to social buy-in.

13 comments:

  1. The blog post you have shared here is god and ethical one. A social relevant content included in this post.
    College paper writing service

    ReplyDelete
  2. Sometime we don't happy because of policies of authorities but we should respect them. We can debate on that but we must should have proper knowledge and proves like best essays writers because we need both of these things to discuss any topic well.

    ReplyDelete
  3. laptop repair and service jaipur
    http://www.jicsindia.com/
    Jics arena training institute – certified it & hardware courses for bright career of students
    Laptop Service Centre in Jaipur is a professional Laptop repair centre, in the Rajasthan offers a comprehensive range of Laptop Services in Jaipur We repair and upgrade services along with friendly customer service. Our team of experienced technicians and hardware engineers can repair, service and upgrade laptop & desktop both.We can have your laptop/desktop problems fixed in less than a day and at times while you wait depends on condition.

    ReplyDelete
  4. Drug Rehab - De-Addiction Treatment Center in Delhi
    http://www.nvsindia.in/
    NVS India is provides treatment and drug rehabilitation for alcohol and drugs addicts. Contact to Nasha Mukti Kendra in delhi, India Call +91 9828155322

    ReplyDelete
  5. Website Design and Web Development Jaipur
    http://www.gitinfosys.com/
    Being a website designing and web development company in Jaipur GIT Infosys will become your end to end partner to get your business online.

    ReplyDelete
  6. 24 hr urgent care
    This is really pretty cool place I like it because it has everything I want more on this blog soon.

    ReplyDelete
  7. What a great blog, thanks for sharing! Wonderful Photos and such a interesting things Send Gifts To pakistan

    ReplyDelete

  8. I read this article. I think You put a lot of effort to create this article. I appreciate your work.
    thesis Writing Service

    ReplyDelete
  9. Well, it’s a nice one, I have been looking for. Thanks for sharing such informative stuff.
    Mergers and Acquisitions consultant

    ReplyDelete
  10. Your blog provided us with valuable information to work with. Each & every tips of your post are awesome. Thanks a lot for sharing. Keep blogging, http://ray-baneyewear2015.com

    ReplyDelete
  11. Dr Itua cure my HIV, I have been a ARV Consumption for 10 years. i have been in pains until i came across Dr Itua on blogs site.I emailed him about my details of my HIV and my location i explained every thing to him and he told me that there is nothing to be scared of that he will cured me, he gave me guarantee,He ask me to pay for items fees so when i'm cured I will show gratitude I did and giving testimony of his healing herbs is what I'm going to do for the rest of you out there having HIV and other disease can see the good work of Dr Itua.I received his herbal medicine through EMS Courier service who delivered to my post office within 5 working days.Dr Itua is an honest man and I appreciate him for his good work.My GrandMa called him to appreciate him and rest of my friends did too,Is a joy to me that I'm free of taking Pills and having that fat belle is a nightmare.you will understand what i'm talking about if you have same problem I was having then not now though.I'm free and healthy Big Thanks To Dr Itua Herbal Center.I have his calendar too that he recently sent me,He Cure all kind disease Like,Cancer,Herpes,Hiv,Hepatitis B,Fibroid,Diabetes,Dercum,Copd ,and also Bring back Ex Lover Back..Here his Contact .drituaherbalcenter@gmail.com Or Whats_app Number +2348149277967

    ReplyDelete